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[ccp4bb]: Re: [ccp4bb] heavy atom pre-soak

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On Sat, 18 Mar 2000, Miguel Ortiz Lombardia wrote:

> Sorry, I clearly misunderstood what Louis Renault proposed about "soaking
> prior to crystallisation". He has kindly sent me a thorough explanation:

i think in some cases the derivatized protein may not crystallize or may
crystallize in a different space group from the native.  the latter is 
a problem for MIR but not for MAD methods.

It is characteristic of thoughtful people that they don't understand some
things that to others are as plain as a pikestaff.  -  A. G. Cairns-Smith
                        David J. Schuller
                        modern man in a post-modern world
                        University of California-Irvine