MAD / MLPHARE

[<naismith@st-andrews.ac.uk>]

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Hi 

Does anyone have a feel for whether MLPHARE will over estimate the FOM 
from its MAD analysis?
Secondly if you include the native and three wavelengths, given the sites 
are all the same XYZ and differ only slightly in AOCC and OCC, how do we 
judge the FOM. 

I kind of worked to the assumption based on HM sites that if two deriv 
occupy the same site MLPHARE overestimates the FOM.

The problem arises in that how do we evaluate whether including 
additional data sets on a MAD problem are really improving things. I know 
look at the map but I also would like to have a computational guide.

Any comments?

best
Jim

James H. Naismith                | Research mailto:naismith@st-and.ac.uk
Centre for Biomolecular Sciences | Teaching mailto:jhn@st-and.ac.uk
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