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[ccp4bb]: Sharpening data
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I am interested in "sharpening" my reflection data by applying an
artificial temperature factor (eg. -70 A**2). This seems non-trivial,
as I am not sure what do with the sigmas. Before you all think I'm
nuts, others have done this in low resolution structures with favorable
results, such as:
Borhani, et al. (Apolipoprotein A-I) PNAS 94:12291-12296.
Stehle, et al. (Simian virus 40) Structure 4:165-182.
Unfortunately, these papers were not so informative as to HOW they
actually did this.
Does anyone have an idea of a program to use that will do this sort of
Thanks very much in advance-