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RE: [ccp4bb]: di-sodium malonate
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Be really careful with this as far as neutralization goes.
McPherson mentioned that the neutralization reaction
(presumably malonic acid/Na-malonate with NaOH) is, as common
sense would indicate as well, rather violent at such high conc
- perhaps ask him directly for details.
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> Subject: [ccp4bb]: di-sodium malonate
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> At the last ACA, Dr. ALexander McPherson gave a talk in which he
> that sodium malonate was an excellent crystallization agent. It was
> reported that it was soluble to 14M. Can anyone tell me what pH is
> necessary to get sodium malonate to this concentration and what
> should it be
> pH'd with?
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