RE: [ccp4bb]: di-sodium malonate

["Bernhard Rupp" <br@llnl.gov>]

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Be really careful with this as far as neutralization goes.
McPherson mentioned that the neutralization reaction 
(presumably malonic acid/Na-malonate with NaOH) is, as common
sense would indicate as well, rather violent at such high conc 
- perhaps ask him directly for details.

BR 

> -----Original Message-----
> From: owner-ccp4bb@dl.ac.uk [mailto:owner-ccp4bb@dl.ac.uk]On Behalf Of
> John Bruning
> Sent: Monday, September 11, 2000 12:14 PM
> To: ccp4bb@dl.ac.uk
> Subject: [ccp4bb]: di-sodium malonate
> 
> 
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> ***    CCP4 home page http://www.dl.ac.uk/CCP/CCP4/main.html    ***
> 
> Hi,
> At the last ACA, Dr. ALexander McPherson gave a talk in which he 
> suggested 
> that sodium malonate was an excellent crystallization agent.   It was 
> reported that it was soluble to 14M.  Can anyone tell me what pH is 
> necessary to get sodium malonate to this concentration and what 
> should it be 
> pH'd with?
> 
> 
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