[ccp4bb]: refinement Q

[Aloka Poddar <aloka@cmb2.saha.ernet.in>]

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Hello all,

We want to refine a theoretically docked  model of an inhibitor-enzyme
complex, using REFMAC or CNS. Can anyone suggest a method where the
constraints (like fixing the torsion/distance etc..) can be applied on a
particular region (i.e. few residues that are involved in the active-site
loop region) in the model? 

In case of REFMAC, how this is done?

Jhimli.