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[ccp4bb]: free R not refining beyond 45%
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Hello,
I am trying to refine a structure (molecular replacement solution) in CNS and
though the map looks very good it does not refine beyond Free R=45% and
crystallographic R=36%. I have two molecules in the assymetric unit. I am also
sure of my space group as this is the only good solution obtained in AMORE
(corr.=59% and R=40%).
If anybody had experienced the same i would be happy to know how to get around
this problem.
thanks,
vibha