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RE: [ccp4bb]: Inhibitors do not show up in electron density maps after soaking
- To: "Zsolt Bocskei" <Zsolt.Bocskei@sanofi-synthelabo.com>
- Subject: RE: [ccp4bb]: Inhibitors do not show up in electron density maps after soaking
- From: "Bernhard Rupp" <br@llnl.gov>
- Date: Tue, 4 Dec 2001 12:23:43 -0800
- Cc: "Ccp4" <ccp4bb@dl.ac.uk>
- Importance: Normal
- In-Reply-To: <"011204182324Z.WT18988. 41*/PN=Zsolt.Bocskei/O=RESEARCH/PRMD=SANOFI/ADMD=ATLAS/C=FR/"@MHS>
- Sender: owner-ccp4bb@dl.ac.uk
- Sensitivity: Personal
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> -----Original Message-----
> Zsolt Bocskei
> Subject: [ccp4bb]: Inhibitors do not show up in electron density maps
> Dear All,
>
> Recently I *have found no* inhibitors bound in an alarmingly large
> portion of the co-crystal structures that I examined. I would be
> grateful if people could send me their comments, experiences etc.
> on this topic.
Recently I *have found* inhibitors bound in an alarmingly large
portion of the co-crystal structures that I examined.
1jky, 1f83, 1fqh ...
Perhaps you are just more in touch with reality....
Best, BR
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Bernhard Rupp
Macromolecular Crystallography and Structural Genomics
LLNL-BBRP L448 Phone (925) 423-3273
University of California Phax (925) 424-3130
Livermore, CA 94551 email br@llnl.gov
URL http://www-structure.llnl.gov
TB Structural Genomics Consortium http://www.doe-mbi.ucla.edu/TB
EU Mirror http://www.ccp14.ac.uk/ccp/web-mirrors/llnlrupp
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