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[ccp4bb]: divalent ion selectivity



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Dear all,

Can any one tell me from the structural point of view 
why some kinases have higher activity with Mg2+ ions, while 
some others prefer Zn2+ or Mn2+.
And what is the meaning for  this kind of divalent ion selectivity?

Thank you very much.

Minghui Li

National Laboratory of Biomacromolecules 
Institute of Biophysics, Academia Sinica 
Tel: 86-10-64888507 
E-mail: lmh@moon.ibp.ac.cn