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[ccp4bb]: Analyze binding pocket hydrophobicity



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We have a ligand that binds to the surface of our enzyme at two sites.
As the ligand exists in both charged and uncharged states, we
would like to analyze the relative hydrophobicities of the two binding
sites.  Does anyone know of programs that we could use to do this, or
something very similar? 
Thanks
Sam Perez-Miller
IUSOM