Last updated: Thu Aug 7 16:10:20 GMT 2006 refmac and related programs version 5.3 is available. It is an intermediate version between 5 and 6. Details of new features will be available soon Very big version for MacOS is also available. 1) Program dimensioned with the following parameters. MAXATOM = 80 000 MAXLINK = 1 000 MAXRESID= 5 000 It should be sufficient for most of the problems. If your protein (including hydrogens) is bigger then you can resize the program: change parameters in the include file atom_com.fh and recompile. 2) You must have ccp4 to compile/use refmac and related programs Note: If you are downloading this version then you need to take the dictionaries also. If you do so then you should do setenv CLIBD_MON dictionary_directory/dic/ after ccp4.setup . Then you can run refmac and libcheck as usual.