News


 20.03.05   BLANC  - new version 

 21.12.04   MOLREP  - new version 9.0 (see documentation)
            SFCHECK - new version 7.0 (see documentation)

. . . . . . . . .

 01.07.02   MOLREP - new version 7.3.02

               * pure rigid body refinement (in patterson or real space)
                 This possibility is useful in the last stage of MR. 
                 For example after fitting the model into EM map. 
                 You can use multi-domain Rigid body refinement.

               * find HA positions by MR solution

               * Self RF for HA position and 
                 Heavy atom search (experimental version)

               * Binaries (executable files) are available:
                 molrep_sgi.gz
                 molrep_alpha.gz
                 molrep_linux.gz

            SFCHECK - 

               * Binaries (executable files) are available:
                 sfcheck_sgi.gz
                 sfcheck_alpha.gz
                 sfcheck_linux.gz

 26.02.02   MOLREP - new version 7.2.0

               * Search model orientation in electron density map 
                 for particular position by phased RF.

               * New possibility for 'Search model in electron density map'
                 With keyword PRF= 'S':
                 1.SAPTF (Spherically averaged phased translation function).
                 2.For current point of SAPTF solution input map is modified,
                   i.e program sets 0 the density outside of sphere with 
                   radius = twice radius of model and with the centre in 
                   current point.    
                 3.usual Rotation function for this modified map.
                 4.Phased Translation functions

 26.11.01   SFCHECK - new version 6.0.2

               No more directory 'dic' and any dictionaries. Now all 
               dictionaries are inside of program. 
               
               * Partial twinning test. 
                 Can create output file with untwinned data.
                 (CIF or MTZ)
               * for omit procedure can create output file
                 with omit phases (CIF or MTZ) 

               * psedo-translation check

 15.07.01   MOLREP - new version 7.1.0

               Main difference from previous version 7.0 /28.02.2001/:
               No more directory 'dic' and any dictionaries. Now all 
               dictionaries are inside of program. 

 28.02.01   MOLREP - new version 7.0.0. (beta-release)

               * five times faster
               * can use EM or electron density map as model or
                 as Fobs (BLANC or CCP4 format)
               * Locked cross rotation function

            BLANC: 

              Total improvement and correction.

              New programs: 

                 ROTDNS     density map rotation

                 CCP42DNS   convert CCP4 density map to BLANC density map

                 DNS2CCP4   converts density map to CCP4 format

 06.11.00   MOLREP - new version 6.2.5.

               * diad search for two different monomers.
               * NMR model can be used.

14.06.00
Home page was created


 02.06.00   MOLREP - version 6.0.4. Correction for Linux.  

 14.04.00   Corrected version 6.0.1 of program MOLREP

 10.04.00   New version 6.0 of program MOLREP

               * diad (or just dimer) search
               * model correction by sequence alignement

            New version of program ALIGN

 19.12.99   
            MOLREP - version 5.4

               * new keyword NOSG - number of new space group if you want 
                 to change space group of file of structure factors.

            new program BLANC_HELP - gives list of blanc's programs with short
                                     description.
 11.11.99   
            MOLREP - version 5.3

               * can just rotate and position the model and compute R-factor,CC
    
                 Use keyword FUN = 'S' and define two files: model 
                 ( keyword FILE_M ) and file of structure factors 
                 ( keyword FILE_F ). Program will rotate ( keyword ANGLES )
                 and position( keyword VPST ) the model and write to output
                 coordinate file. Also compute R-factor and Correlation
                 Coefficient.

            TRANS - ortogonal transformation of atomic coordinates.
                    new keyword SMODE 

                    SMODE:  <O>/F  -  O - shifts in orthogonal system
                                      F - shifts in fractional

 24.10.99   
            MOLREP - version 5.2
               * new keyword FILE_T. Program creates file of list of peaks 
                 of rotation function or reads this file. File name is
                 defined by keyword FILE_T. Default is 'molrep_rf.tab' 

               * new style of output of RF and TF, like:

                    Sol_RF 36    89.82   66 ......
                    Sol_TF_4  1    0.00  180......

                 useful for grep command. See ../molrep/doc/test.doc

            MIR version 4.1 

               * if input file was MTZ program creates new MTZ file
               * with Fobs and phases.

            New program BLANC2MTZ:

               * writes a contents of internal BLANC files: Fobs, Fcalc, 
               * Phases to new MTZ file. The exit from program suite BLANC.

 04.09.99   New version of program ALIGN

              alignes optimally 2 aminoacid sequences. Two files can be
              PDB or BLANC coordinate file or just ASCII file of sequence. 
              Program writes output file which is poly-alanine 
              model for first file with coordinates from second according
              to the alignement.

              File with sequence is ASCII file:

              ! 
              !# sequence 
              !SVIGSDDRTRVTNTTAYPYRAIVHISSSIGSCTGWMIGPKTVATAGHCIY
              !# this is comment
              !    DTSSG--SFAGTATVSP   GRNGTSYPYG
              !NRGTRITKEVFDNLTNWKNSAQ

              If first symbol in the line is "#" it means the line is comments
              Blancs are ignored.
      
            New program TWIN

              *perfect and partial hemihedral twinning test
              *can create output file with detwined data

 18.07.99   New program SFVSUM


               sum two vectors of structure factors: (F1 + scale*F2)
               or convolution: F1(h)*scale*F2(-h)

            MOLREP - version 5.1

               new possibilities for keyword SURF:    

               SURF: <N>,Y,A,O - means to do the model correction. 
                      
                      O - only shift to the origin.
                      A - polyalanine model and all B = 20, remove from model
                          water molecules, H atoms, atoms with alternative 
                          position (except first), atoms with occupacy = 0,
                          shift to the origin.
                      Y - remove from model water molecules, H atoms, atoms
                          with  alternative position (except first), atoms
                          atoms with occupacy = 0 ,  shift to the origin,
                          to compute atomic accessible surface area and
                          replace atomic B to 
                          B = 15.0 + SURFACE_AREA*10.0 

 21.06.99   New program F2CIF

               writes a contents of internal BLANC files: Fobs, Fcalc, Phases 
               to one output formatted CIFile. The exit from program 
               suite BLANC.

            MOLREP - new version 5.0

               * Spherically averaged phased translation function.
               * Phased Rotation and Phased Translation functions.
               * fitting two models.

            SFCHECK 

               * perfect twinning test

 10.04.99   Modified files blanc_descr.txt and README
    
            New program CONSEQ - converts sequence to coordinate file 
            which can be used for ALIGN.

            New version and arragement of MIR, TRAHALO, MIR_II:

            * independent from BLANC version of MIR
              Now MIR is main program, others can be used only if their
              input files are in BLANC format. We can have it after MIR.
              TRAHALO has a lot of possibilities. 

            * all program are in unique tar file: mir.tar.gz

            * MIR has ccp4 version which uses MTZ file

            * more peaks to check, up to 20

            * can take into account pseudo-translation

            * three times faster 

            * MIR , TRAHALO can be used for SAD case

            * more in blanc/mir/README

 13.03.99   New version of MOLREP   /Vers 4.1; 09.03.99/

            * If keywords FUN = 'R' and LIST = 'L' program computes and 
              writes to molrep.doc all symmetry realated peaks of Rotation 
              Function.

            * If keywords FUN = 'R' and LIST = 'L' program computes list 
              of peaks of Patterson and writes to molrep.doc. It may be useful
              to detect pseudo-translation.

            * New keyword LMIN ( see README )

 09.12.98   New version of MOLREP   /Vers 4.0; 09.12.98/
            New feature: 

            * can check and manage pseudo-translation.

            * check more peaks of rotation and translation function, up to 50.

            * default MODE='F' is three times faster

            * after Rotation Function program creats file "molrep_rf.tab" 
              with list of peaks of RF. You can edit and use this file
              instead of compute RF again.
                   
            * can do the model correction. Correction means to remove 
              from model water molecul, H atoms, atoms with alternative 
              position (except first), atoms with occupacy = 0 , to compute
              atomic accessible surface area and replace atomic B to 
              B = 15.0 + SURFACE_AREA*10.0 

            new README file

 01.09.98   TRAHALO, SIR - correction for SAD case.

 26.08.98   Improvement and correction in example programs
            New file blanc/prog/README - how to use BLANC subroutines to
            write program.

            New program "fminusf" - computes ! !F1! - scale * !F2! !

            MOLREP - new keyword "P2" - experimental option, if P2 (percent of
                     model_2) > 0 than program uses 
                    !!Fobs!-!Fmod2!*(P2/100)! instead of !Fobs! for RF
            

 13.08.98   Improvement and correction: 
               align  - writes two output files which are suitable
                        for FIT program. 
               fit    - can use files from ALIGN program
               rotlsq - computes Rfree
               angsum - correction 
               readPDB - now use insertion code correctly.

 04.08.98   Some bugs removed.
            Improvement programs:
               makecif, libcheck, emin, modcheck
               sfcheck
               mir,sir,trahalo 
            New version: SFCHECK       see README

 02.06.98   New method of the getting BLANC. Now there is only one tar-file 
            for getting BLANC. See README

            Much more improvements in makecif, libcheck, emin, modcheck

            Correct TRPACK for Phased translation function.
            Phased Fast Rotation function was reconstructed.  

 28.04.98   New order of messages. Now new message will be first.

            Check all program for linux system. A lot of correction (small)
            in all programs. New makefiles.
            Please replace old version of BLANC.
 13.03.98 


         1. New programs:

            ROTFFT        rigid body refinement by FFT. 

         2. New version:

            SFCHECK       see README

            MOLREP        see README, can create PostScript file with 
            CROSSROT      a picture of self or cross rotation function.
            SELFROT
            TRFUN            

 19.12.97 


         1. New programs:

            SF_CALC       computes Structure factors by formula for
                          atomic model, can use atomic aniso B factors. 

            ANISOSCL      calculates anisothermal scaling of two files.
                          completely new correct version.

            GENDEN_ANISO  generates electron density for atomic
                          model with aniso B factors.

            DNS2CCP4      converts density map to CCP4 format


         2. SFCHECK       new version with anisothermal scaling.     
                          Can use atomic aniso B factors.
 
         3. more blanc_descr.txt

 11.09.97 
                          
         1. Correction and improvement in:

            libsubr.ftn:
            libutils.ftn:

            in programs : 
                         peaksrch.f
                         concrd.f
            in superprograms : 
                         trahalo.f (new name instead of pattsrch.f)
                         molrep  - ccp4 version which can read MTZ file.
                         sfcheck - ccp4 version which can read MTZ file.     

         2. New programs:
                       risoline
                       angsum
                       mtz2cif   - reads MTZ file and writes CIFile.

         3. Dictionary correction:
            
              ener_lib.cif
              mon_lib.cif
              symlib.blc   for space group F432 and F4132

         4. more blanc_descr.txt


        --- change location to YORK ---

 14.02.97 

         Global improvement and correction for all programs.
         Now you can use BLANC for DEC alpha computer.
         New versions of superprograms: SFCHECK, MMM, MOLREP, MIR, SIR,
         PATTSRCH, MAKECIF, MODCHECK, LIBCHECK, EMIN, DENMOD
         CONTACT.
         New versions of programs: PSCALE, HISTOGRM, WATPEAKS

 12.01.97 
                          
         1. Correction in:

            libsubr.ftn:

            in programs : 
                         readPDB.f
                         lookfl.f
            in superprograms : 
                         molrep 
                         MIR
                         denmod

         2. New version / "ver. 1.0 12.01.97" / :

              makecif
              modcheck
              libcheck
              emin

         3. Dictionary correction:
            
              ener_lib.cif
              mon_lib.cif

         4. more blanc_descr.txt

 30.12.96 

            more blanc_descr.txt

            new file: blanc/README

 24.11.96 
            a lot of improvements and corrections and new possibilities
            in programs : 

                   makecif  - see README file in blanc/make
                   libcheck

            new programs : 

            MIR - atomatical heavy atom solution. Now is completely new.
                  computes the phases of native structure factors by use
                  information of several derivatives. Can use the phases
                  from other sources. Can use anomalous scattering,
                  refines phases by modification density /solvent flattening/

            EMIN - energy minimization / or B_factor regularization / 
                   minimizes the energy of structure using the restraints files
                   from program MAKECIF. see README file in blanc/make
                     
            MMM  - Macro Molecular Minimization.
                   Minimizes difference between observed electron density map
                   and map of atomic model. Uses the restrains files from 
                   program MAKECIF.
                   Program runs good enouph but this is just preliminary 
                   version. I am going to completely change X_ray part.

 20.10.96 

            a lot of improvements and corrections and new possibilities
            in programs : 

                   makecif  - see README file in blanc/make
                   modcheck
                   libcheck

            sfcheck - now can read blanc-system files. 
                      Program "checksf" for blanc-system files is deleted. 

            denmod  - new version which uses packing function when create
                      envelope.

            a lot of small correction in the other programs.

 06.10.96 
                          
          Correction and improvement in:

            libutils.ftn
            libsubr.ftn

            pattsrch
            sir
            isoline

            
            Library mon_lib.cif was corrected for latest proposal mmCIF.

            sfcheck and checksf   - new possibility:  
                                    you can have local estimation
                                    for map calculated with omit refinement
                                    phases, i.e phases calculeted from 
                                    total omit map (see program "omit")
                                    New parameter NOMIT - number of 
                                    cycles omit_procedure. 0 - means without
                                    this posibility, 2 - is good.

            new programs : makecif  - see README file in blanc/make
                           modcheck
                           libcheck

                           contact  - see README file in blanc/contact
                                      the same program as "contact" in
                                      blanc/for , but reads PDB_file and
                                      writes to PDB_file instead of 
                                      blanc_crd files.
 16.09.96 
            New program CONDEN - converts XY_map to YZ_map or XZ_map.

            Correction in ISOLINE.
 14.09.96 

          All programs and libraries was corrected for latest proposal
          mmCIF.

          Correction and improvement in:

            libutils.ftn
            libsubr.ftn

            toblanc
            readPDB
            writePDB
            contact  - two times faster
            peaksrch
            pattsrch
            sir
            concrd   - new possibility:  convert ort. coords to fract.
                                           and   fract.coord to ort.

            New program ISOLINE (draft) - creates PostScript file of electron
            density map.
 22.08.96 

          Now SFCHECK and CHECKSF create PostScript file.

          ftp_anonymous_user contains compressed files. Use command 
          "uncompress". 
          Change file: ftp.bat. Now ftp.bat creates subdirectories,  
          copies files from ftp_anonymous_user and uncompresses all files.  

 23.06.96 

          All programs and libraries was corrected for latest proposal
          mmCIF.

          Correction: 
             programs:  TOBLANC

          A little more in blanc_descr.txt about input and output CIFiles.

 12.06.96 

          remove program: PATT_SCALE , use now only PSCALE

          Correction: 

             all super_program. 
             program: COPYFL, PSCALE

          Rename "symlib.sym" to "symlib.blc"

 07.06.96 total revision all programs.

          Now all files of sructure factors, phase, coefficients, density
          have file extension "dat". So when you tape file name for program
          request you need not tape the extention. Program add the extention
          automatically.
          
          New super_program CHECKSF - as SFCHECK only for BLANC_coordinates file
          and internal BLANC structure factors file. Now SFCHECK  - checks 
          agreement PDB coordinates file and PDB structure factors file.

          New program CHECK_CRD - gets information about file "crd".
          This possibility was removed from readPDB.

          Correction: 
             super_programs:  PATTSRCH, SIR, MIR
             programs: CONTACT, readPDB, writePDB, SORTMRG, PEAKSRCH

 21.05.96 
          improve pattsrch
                  sir
          new program: CONTACT - computes inter or/and intra molecular contacts.

 12.05.96 
          correction:
              libutils.ftn
              libsubr.ftn:
                          refine

 06.05.96 new version: sir     
                       mir
                       pattsrch
          correction:
              libutils.ftn
              libsubr.ftn:
                          phase
                          abcdph
                          phabcd
            more blanc_descr.txt

 24.04.96  correction:
              libsubr.ftn:
                          peaksrch
                          phase
              super_programs:      
                          sfcheck   
                          denmod
                          sir
                          pattsrch
                          molrep

 17.04.96   new program: pscale
            improve libsubr.ftn
                    super_programs:
                      denmod
                      omit
                      omit_map
                      sir
                      pattsrch
            more blanc_descr.txt

 15.04.96 - libutils.ftn: new subroutine GET_NSYMZ.
            libsubr.ftn: a lot of corrections. 
            Improvement programs:
               molrep 
               crossrot
               trfun
               trpack
               selfrot
               sfcheck - add distribution of B-factor per residue
            new programs:
               writePDB - instead of this possibility in program CONCRD 
               copyold  - instead of this possibility in program CONCRD 
               rfadd
               rfrot
               surface
            blanc_descr.txt - a little more.


 23.03.96 - create this file.

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