The Free-Fourier Duck
For the purposes of cross validation we may chose to omit some of our
data.
If 10% of the reciprocal space data are omitted at random, then the
following images are obtained:

If 10% of the reciprocal space data are omitted in thin spherical
shells, then the following images are obtained:

Crystallographic Interpretation:
Using Free-Reflections is a good validation of coordinate
refinement, but is unwise when calculating maps. Particular care must
be taken when using free-sets in density modification calculations,
as the absence of the free-set can systematically bias the rest of the
data.
More Fourier transforms.
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