| PDB Code | PDB Info | Protein | Source | E.C. no. | Res./Å
| R-factor | Inhibitor | Covalent | Inhibitor bound in active site
|
| 1TON | View | Tonin | Rattus rattus | Not Assigned | 1.8 | - | None | - | - |
|
| 1HCG | View | Blood Coagulation Factor XA | Homo sapiens | - | 2.2 | 16.8 | None | - | - |
|
| 3RP2 | View | Rat Mast Cell Protease II | Rattus rattus | - | 1.9 | 19.1 | None | - | - |
|
| 2KAI | View | Kallikrein A | Sus scrofa | 3.4.21.34 | 2.5 | 22.4 | Bovine pancreatic trypsin inhibitor | No | View |
|
| 2PKA | View | Kallikrein A | Sus scrofa | 3.4.21.34 | 2.05 | 22.0 | Benzamidine | No | View |
|
| 1TRN | View | Trypsin | Homo sapiens | 3.4.21.4 | 2.2 | 17.7 | Diisopropyl-Fluorophosphofluoridate (DFP) | Yes | View |
|
| 1SGT | View | Trypsin | Streptomyces griseus (Strain K1) | 3.4.21.4 | 1.7 | 23.0 | None | - | - |
|
| 1BIT | View | Trypsin (Anionic) | Salmo salar | 3.4.21.4 | 1.83 | 19.9 | Benzamidine | No | View |
|
| 2TBS | View | Trypsin | Salmo salar | 3.4.21.4 | 1.8 | - | Benzamidine Inhibitor | No | View |
|
| 1BRA | View | Trypsin (D189G, G226D) | Rattus rattus | 3.4.21.4 | 2.2 | 15.6 | Benzamidine | No | View |
|
| 1BRB | View | Trypsin (D189G, G226D) | Rattus rattus | 3.4.21.4 | 2.1 | 19.8 | BPTI Variant (C5A, C55A) | No | View |
|
| 1BRC | View | Trypsin (D189G, G226D) | Rattus rattus | 3.4.21.4 | 2.5 | 16.8 | Amyloid Beta-Protein Precursor Inhibitor Domain (APPI) | No | View |
|
| 1TRM | View | Trypsin (D102N) | Rattus rattus | 3.4.21.4 | 2.3 | 16.0 | Benzamidine at pH 6 | No | View |
|
| 2TRM | View | Trypsin (D102N) | Rattus rattus | 3.4.21.4 | 2.8 | 15.7 | Benzamidine | No | View |
|
| 1EPT | View | E-Trypsin | Sus scrofa | 3.4.21.4 | 1.8 | 18.4 | None | - | - |
|
| 1MCT | View | Trypsin | Sus scrofa | 3.4.21.4 | 1.6 | 16.7 | Inhibitor from Bitter Gourd | No | View |
|
| 1NTP | View | Trypsin (N48D, N95D & N115D) | Bos taurus | 3.4.21.4 | 1.8 | 18.7 | Monoisopropylphosphoryl Inhibitor | Yes | View |
|
| 1PPC | View | Trypsin | Bos taurus | 3.4.21.4 | 1.8 | 18.1 | NAPAP | No | View |
|
| 1PPE | View | Trypsin | Bos taurus | 3.4.21.4 | 2.0 | 15.1 | Trypsin Inhibitor (CMTI-I) | No | View |
|
| 1PPH | View | Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 16.7 | 3-TAPAP | No | View |
|
| 1SMF | View | Trypsin | Bos taurus | 3.4.21.4 | 2.1 | 19.0 | Bowman-Birk Inhibitor | No | View |
|
| 1TAB | View | Trypsin | Bos taurus | 3.4.21.4 | 2.3 | 20.0 | Bowman-Birk Inhibitor (AB-I) | No | View |
|
| 1TNG | View | Trypsin | Bos taurus | 3.4.21.4 | 1.8 | 17.2 | Aminomethylcyclohexane | No | View |
|
| 1TNH | View | Trypsin | Bos taurus | 3.4.21.4 | 1.8 | 16.8 | 4-Fluorobenzylamine | No | View |
|
| 1TNI | View | Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 16.1 | 4-Phenylbutylamine | No | View |
|
| 1TNJ | View | Trypsin | Bos taurus | 3.4.21.4 | 1.8 | 17.0 | 2-Phenylethylamine | No | View |
|
| 1TNK | View | Trypsin | Bos taurus | 3.4.21.4 | 1.8 | 17.1 | 3-Phenylpropylamine | No | View |
|
| 1TNL | View | Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 16.4 | Tranylcypromine | No | View |
|
| 1TPA | View | Anhydro-Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 17.5 | Pancreatic Trypsin Inhibitor | No | View |
|
| 1TPS | View | Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 16.2 | A90720A | No | View |
|
| 2PTN | View | Trypsin | Bos taurus | 3.4.21.4 | 1.55 | 19.3 | None | - | - |
|
| 2TLD | View | Trypsin | Bos taurus | 3.4.21.4 | 2.6 | 17.3 | Streptomyces Subtilisin Inhibitor (M70G,M73K) | No | View |
|
| 3PTN | View | Trypsin | Bos taurus | 3.4.21.4 | 1.7 | 19.8 | None | - | - |
|
| 1GBT | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 2.0 | 16.2 | Guanidinobenzoylated at serine 195 | Yes | View |
|
| 1TLD | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 1.5 | 16.7 | None | - | - |
|
| 1TPO | View | Beta-Trypsin (pH 5) | Bos taurus | 3.4.21.4 | 1.8 | 18.0 | None | - | - |
|
| 1TPP | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 1.4 | 19.1 | P-Amidino-Phenyl-Pyruvate (APPA) | Yes | View |
|
| 1TYN | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 2.0 | 16.9 | Cyclotheonamide A | Yes | View |
|
| 2PTC | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 1.9 | 18.7 | Pancreatic Trypsin Inhibitor | No | View |
|
| 3PTB | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 1.7 | 18.2 | Benzamidine at pH 7 | No | View |
|
| 4PTP | View | Beta-Trypsin | Bos taurus | 3.4.21.4 | 1.34 | 17.1 | Diisopropylphosphoryl Inhibitor | Yes | View |
|
| 1ACB | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.0 | 16.7 | Eglin-C | No | View |
|
| 1CHO | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.8 | 16.8 | Turkey Ovomucoid Third Domain | No | View |
|
| 2CHA | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.0 | - | P-Toluene sulfonate | Yes | View |
|
| 4CHA | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.68 | 19.8 | None | - | - |
|
| 5CHA | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.67 | 17.9 | None | - | - |
|
| 6CHA | View | Alpha-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.8 | 20.0 | Phenylethane Boronic Acid | Yes | View |
|
| 1GCD | View | Gamma-Chymotrypsin (pH 5.6) | Bos taurus | 3.4.21.1 | 1.9 | 18.7 | Diethyl Phosphoryl | Yes | View |
|
| 1GCT | View | Gamma-Chymotrypsin A (pH 7) | Bos taurus | 3.4.21.1 | 1.6 | 17.3 | Tetrapetide (Autolytic cleavage product) | Yes | View |
|
| 1GHA | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.2 | 16.4 | Tetrapetide (Autolytic cleavage product) | Yes | View |
|
| 1GHB | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.0 | 15.2 | N-Acetyl D-Tryptophan | No | View |
|
| 1GMC | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.2 | 17.6 | Tetra-Peptide (Autolytic cleavage product) | Yes | View |
|
| 1GMD | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.2 | 17.6 | Pentapeptide Tetrahedral Intermediate | Yes | View |
|
| 1GMH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.1 | 18.7 | Diisopropylphosphorofluoridate | Yes | View |
|
| 2GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.9 | 18.1 | None | - | - |
|
| 2GCT | View | Gamma-Chymotrypsin (pH 2) | Bos taurus | 3.4.21.1 | 1.8 | 16.9 | Tetra-Peptide (Autolytic cleavage product) | Yes | View |
|
| 2GMT | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.8 | 18.8 | N-Ace-L-Ala-L-Phe-Alpha-Chloroethylketone | No | View |
|
| 3GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.9 | 20.3 | Trans-O-Hydroxy-Alpha-Methyl Cinnamate | Yes | View |
|
| 3GCT | View | Gamma-Chymotrypsin A(pH 10.5) | Bos taurus | 3.4.21.1 | 1.6 | 17.3 | Tetrapetide (Autolytic cleavage product) | Yes | View |
|
| 4GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.9 | 20.9 | P-Diethylamino-O-Hydroxy-Alpha-Methyl Cinnamate | Yes | View |
|
| 5GCH | View | Gamma-Chymotrypsin (Photolysis Product) | Bos taurus | 3.4.21.1 | 2.7 | 15.6 | P-Diethylamino-O-Hydroxy-Alpha-Methyl Cinnamate | No | View |
|
| 6GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 2.1 | 18.0 | N-Acetyl-L-Phenylalanyl Trifluoromethyl Ketone | Yes | View |
|
| 7GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.8 | 19.0 | N-Acetyl-L-Leu-L-Phe Trifluoromethyl Ketone | Yes | View |
|
| 8GCH | View | Gamma-Chymotrypsin | Bos taurus | 3.4.21.1 | 1.6 | 19.3 | Gly-Ala-Trp | Yes | View |
|
| 1EAS | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 18.3 | 3-[[(Methylamino) Sulfonyl]Amino]-2-Oxo-6-Phenyl -N-[3,3,3-Trifluoro-1-(1-Methylethyl)-2-Oxopropyl] -1(2H)-Pyridineacetamide | Yes | View |
|
| 1EAT | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.0 | 16.7 | 2-[5-Methanesulfonylamino-2-(4-Aminophenyl)i -6-Oxo-1,6-Dihydro-1-Pyrimidinyl]-N- (3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl)Acetamide | Yes | View |
|
| 1EAU | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.0 | 16.1 | 2-[5-Amino-6-Oxo-2-(2-Thienyl)- 1,6-Dihydropyrimidin-1-yl)-N-[3,3-Difluoro-1-Isopropyl-2 -Oxo-3-(N-(2-Morpholinoethyl) Carbamoyl]Propyl]Acetamide | Yes | View |
|
| 1ELA | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 18.5 | Trifluoroacetyl-L-Lysyl-L-Prolyl-P-Isopropylanilide | No | View |
|
| 1ELB | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.1 | 15.0 | Trifluoroacetyl-L-Lys-L-Leu-P-Isopropylanilide | No | View |
|
| 1ELC | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.75 | 15.0 | Trifluoroacetyl-L-Phe-P-Isopropylanilide | No | View |
|
| 1ELD | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 19.6 | Trifluoroacetyl-L-Phe-L-Ala-P-Trifluoromethylaninide | No | View |
|
| 1ELE | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 17.1 | Trifluoroacetyl-L-Val-L-Ala-P-Trifluoromethylaninide | No | View |
|
| 1ELF | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.7 | 18.0 | N-(Tert-Boc-Ala-Ala)-O-(P-Nitrobenzoyl) Hydroxylamine | Yes | View |
|
| 1ELG | View | Elastase (pH 5) | Sus Scrofa | 3.4.21.36 | 1.65 | 17.0 | N-(Tert-Boc-Ala-Ala)-O-(P-Nitrobenzoyl) Hydroxylamine | Yes | View |
|
| 1ESA | View | Elastase (-45C Form) | Sus Scrofa | 3.4.21.36 | 1.65 | 19.0 | None | - | - |
|
| 1ESB | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.3 | 21.0 | N-Carbobenzoxy-L-Ala-P-Nitrophenol Ester | No | View |
|
| 1INC | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.94 | 17.2 | Benzoxazinone Inhibitor | Yes | View |
|
| 1JIM | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.31 | 15.3 | 3-Methoxy-4-Chloro-7-Aminoisocoumarin | Yes | View |
|
| 2EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.5 | 21.0 | Trifluoroacetyl-L-Lys-L-Ala -P-Trifluoromethylphenylanilide | No | View |
|
| 3EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.65 | 16.9 | None | - | - |
|
| 4EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.78 | 16.0 | Ace-Ala-Pro-Val-Difluoro-N-Phenylethylacetamide | Yes | View |
|
| 5EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 2.09 | 15.0 | Carbobenzoxy-Ala-Isoleucylboronic Acid | Yes | View |
|
| 6EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 20.0 | Dimethylformamide | No | View |
|
| 7EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.8 | 19.0 | Trifluoroacetyl-L-Leu-L-Ala -P-Trifluoromethylphenylanilide | No | View |
|
| 8EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.78 | 17.0 | Guanidinium Isocoumarin | Yes | View |
|
| 9EST | View | Elastase | Sus Scrofa | 3.4.21.36 | 1.9 | 17.1 | Guanidinium Isocoumarin | Yes | View |
|
| 1EST | View | Tosyl-Elastase | Sus Scrofa | 3.4.21.36 | 2.5 | - | P-Toluenesulfonyl | Yes | View |
|
| 1HNE | View | Human Neutrophil Elastase | Homo sapiens | 3.4.21.37 | 1.84 | 16.4 | Methoxysuccinyl-Ala-Ala-Pro-Ala Chloromethyl Ketone | No | View |
|
| 1PPF | View | Human Leukocyte Elastase | Homo sapiens | 3.4.21.37 | 1.8 | 16.6 | Third Domain of Turkey Ovomucoid Inhibitor | No | View |
|
| 1PPG | View | Human Leukocyte Elastase | Homo sapiens | 3.4.21.37 | 2.3 | 14.5 | Meo-Succinyl-Ala-Ala-Pro-Val Chloromethylacetone | Yes | View |
|
| 1ABI | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 13.2 | Hirulog 3 | No | View |
|
| 1ABJ | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.4 | 14.4 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1DWB | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.16 | 15.1 | Benzamidine | No | View |
|
| 1DWC | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.0 | 15.0 | MD-805 (Argatroban) | No | View |
|
| 1DWD | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.0 | 15.6 | NAPAP | No | View |
|
| 1DWE | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.0 | 16.4 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1FPC | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 14.7 | DAPA | No | View |
|
| 1FPH | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.5 | 16.6 | Fibrinopeptide A | Yes | View |
|
| 1HAI | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.4 | 13.9 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1HAH | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 11.4 | None | - | - |
|
| 1HBT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.0 | 18.1 | A Peptidyl Pyridinium Methyl Ketone | Yes | View |
|
| 1HGT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.2 | 16.7 | None | - | - |
|
| 1HLT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.0 | 14.6 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1HUT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.9 | 15.9 | D-Phe-Pro-Arg-CH2 | No | View |
|
| 1IHS | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.0 | 16.9 | Hirutonin-2 | No | View |
|
| 1IHT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.1 | 16.2 | Hirutonin-6 | No | View |
|
| 1NRN | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.1 | 17.9 | Receptor based peptide NRS | No | View |
|
| 1NRO | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.1 | 17.1 | Receptor based peptide NRP | No | View |
|
| 1NRP | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.0 | 19.9 | Receptor based peptide NR'S | No | View |
|
| 1NRQ | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.5 | 21.7 | Receptor based peptide D-FPR'S | No | View |
|
| 1NRR | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.4 | 14.5 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1NRS | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.4 | 14.6 | Receptor based peptide NRP (1st 4 residues) | No | View |
|
| 1PPB | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 1.92 | 15.6 | D-Phe-Pro-Arg-CH2 | Yes | View |
|
| 1THR | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 15.5 | None | - | - |
|
| 1THS | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.2 | 16.1 | None | - | - |
|
| 1TMB | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 13.8 | Cyclotheonamide A | Yes | View |
|
| 1TMT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.2 | 17.7 | CGP 50,856 | No | View |
|
| 1TMU | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.5 | 20.2 | D-Phe-Pro-Arg-Chloromethylketone | Yes | View |
|
| 2HAT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.5 | 14.3 | Fibrinopeptide A Mimic | No | View |
|
| 2HGT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.2 | 16.3 | Hirulog I | No | View |
|
| 2HPP | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.3 | 15.7 | D-Phe-Pro-Arg-CH2 | No | View |
|
| 2HPQ | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 3.3 | 15.5 | D-Phe-Pro-Arg-CH2 | No | View |
|
| 3HAT | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.5 | 14.0 | Fibrinopeptide A Mimic | No | View |
|
| 4HTC | View | Alpha-Thrombin | Homo sapiens | 3.4.21.5 | 2.3 | 17.3 | Hirudin (Variant 2, Lys 47) | No | View |
|
| 2HNT | View | Gamma-Thrombin | Homo sapiens | 3.4.21.5 | 2.5 | 15.6 | None | - | - |
|
| 1BBR_b | View | Alpha-Thrombin | Bos taurus | 3.4.21.5 | 2.3 | 16.7 | Fibrinopeptide Alpha(Residues 7-16) | No | View |
|
| 1BBR_c | View | Alpha-Thrombin | Bos taurus | 3.4.21.5 | 2.3 | 16.7 | Fibrinopeptide Alpha(Residues 7-16) | No | View |
|
| 1HRT | View | Alpha-Thrombin | Bos taurus | 3.4.21.5 | 2.8 | 15.5 | Hirudin Variant-1 | No | View |
|
| 1BBR_a | View | Epsilon-Thrombin | Bos taurus | 3.4.21.5 | 2.3 | 16.7 | Fibrinopeptide Alpha(Residues 7-16) | No | View |
|
| 1ETT | View | Epsilon-Thrombin | Bos taurus | 3.4.21.5 | 2.5 | 16.7 | 4-TAPAP | No | View |
|
| 1ETR | View | Epsilon-Thrombin | Bos taurus | 3.4.21.5 | 2.2 | 17.5 | MQPA | No | View |
|
| 1ETS | View | Epsilon-Thrombin | Bos taurus | 3.4.21.5 | 2.3 | 17.8 | NAPAP | No | View |
|
Trypsin protein structures. 1trn (Human), 1sgt (Streptomyces griseus), 2tbs (Salmon), 2trm (Rat), 1mct (Porcine) and 2ptn (Bovine).