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Re: [ccp4bb]: NCS with molecular replacement
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On Tue, 25 Apr 2000, Jeff Taylor wrote:
> I have a rather sticky molecular replacement problem and I'm looking for
> helpful ideas. My protein crystallizes in the C2 space group, although
> homologs of this protein crystallize in P61.
> Has anyone worked out a way to
> take advantage of a NCS in a molecular replacement search?
yes. see Tong and Rossmann (1990) Acta Cryst A46 for a description of a
"locked rotation function", which is implemented in an application called
AMoRe has a locked rotation feature now, but i do not yet have any
positive experience with it.
"We are going to die, and that makes us the lucky ones" - Richard Dawkins
David J. Schuller
modern man in a post-modern world
University of California-Irvine