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[ccp4bb]: P1 or C2 or ?

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I would integrate in P1.  You can then scale/average with scalepack in the 
different space groups (P1 or C1 or C2) using the matrix command.  If there is 
a problem with indexing as Harry Powell suggests, then you will have trouble, 
even in P1, with high R(merge).

Bernie Santarsiero