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[ccp4bb]: Postdoctoral Position at Baylor College of Medicine, USA

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Two postdoctoral positions are available in the Department of Bio-
chemistry and Molecular Biology at Baylor College of Medicine (BCM). 
A current focus of the group is to investigate the structural basis 
of transcription initiation and regulation in Eukarya. Our goal is 
to understand the underlying mechanism of co-operative DNA binding 
and signal transduction by transcriptional co-activators, and its
implication in human pathogeneses. Well-diffracting crystals are at
hand for some of these projects.

The first position is ideally suited for a protein X-ray crystal-
lographer with demonstrated experience in macromolecular crystal-
lography using MAD/MIR. Experience with protein purification and 
molecular biology techniques is a great advantage. The second po-
sition is available for a molecular biologist/protein chemist with
experience in methods used to study nucleic acid-binding proteins 
(e.g. gel-shift assay, site-directed mutagenesis). Experience with 
the overexpression and purification of proteins is desirable.

The two positions are available for a period of three years. Applicants 
should have a recent Ph.D. in biological sciences, chemistry, or a 
closely related field. The salary range for both positions is highly 
competitive, and will be in addition to a generous fringe benefit

U.S. News & World Report has recently ranked BCM among the top 12 
medical schools in the United States. Our lab is fully equipped for 
all aspects of protein X-ray crystallography (including two high-end
Silicon Graphics Octane2 workstations), protein chemistry, and molecular
biology. State-of-the-Art X-ray data collection facilities are also 
available on-site. In addition, BCM is also part of the Gulf Coast 
Protein Crystallography Consortium (GCPCC), which operates the newly 
build protein crystallography MAD beamline at the Center for Advanced 
Microstructures and Devices (CAMD) in Baton Rouge, Louisiana. Ample
opportunities for collaborative work within BCM and the National Center
for Macromolecular Imaging are also available.

Informal inquiries are encouraged. Please send a current resume, and the
names and addresses of three referees to: Dr. Francis Tsai, Department of
Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor
Plaza, BCM-315B, Houston, TX 77030, USA. Tel: (713) 798-8668, Fax: (713)
796-9438, E-mail: ftsai@bcm.tmc.edu.

 Francis T.F. Tsai, D.Phil.
 Assistant Professor
 Department of Biochemistry & Molecular Biology
 Baylor College of Medicine Tel: +1 713 798-8668 (Office)
 One Baylor Plaza, BCM-315B Tel: +1 713 798-8565 (Lab)
 Houston, TX 77030-3498 Fax: +1 713 796-9438
 USA Email: ftsai@bcm.tmc.edu