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[ccp4bb]: Biochemistry Research Associate at Abbott Bioresearch Center, Inc.
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Research Associate - Biochemistry (Position Code: Biochem 03)
A new research associate position is available in the structural biology group
at Abbott Bioresearch Center in Worcester, MA, located 45 minutes west of
Boston. Abbott Bioresearch Center, a division of Abbott Laboratories, has
vibrant research programs on traditional, low molecular weight pharmaceuticals
and fully-human, monoclonal antibody pharma-ceuticals in the immunology and
oncology therapeutic areas. The structural biology group is fully-integrated
into the drug design process at ABC, and exciting opportunities for both
scientific and career development exist.
The successful candidate will conduct protein purification and characterization
in support of structural biology efforts. Assistance in the development or
execution of enzyme assays will likely be required. The opportunity exists to
become involved in protein crystal growth experiments. Requirements: B.S. or
M.S. in Biochemistry, Chemistry, Molecular Biology, or equivalent. At least one
year of hands-on laboratory experience in protein purification and
characterization, including affinity chromatography, and basic enzyme kinetics
is required. Experience in simple molecular biology techniques and fermentation
(E. coli, yeast, baculovirus) is a plus, as is experience in protein
crystallization. Experience in a pharmaceutical or biotechnology environment is
The protein crystallography laboratory at Abbott Bioresearch Center is equipped
with a Nonius FR571 x-ray generator, MarResearch CCD and MAR345 image plate
detectors, Osmic optics, and Oxford Cryostream cryogenics. We also have routine
access to the IMCA-CAT beamlines at the Advanced Photon Source, Argonne National
Laboratory. Ample computational resources are available, and the structural
biology group at ABC is committed, along with our sister group at Abbott Park,
IL, to the automation of the routine crystallographic tasks using
state-of-the-art robotic systems.
Applicants should submit their curriculum vitae, listing names and contact
information for three references, by e-mail to firstname.lastname@example.org (MS
Word, PDF, or plain text, please), ensuring that the Position Code "Biochem 03"
and "David Borhani" are prominent in the Subject line.
Group Leader, Biochemistry
Abbott Bioresearch Center, Inc.
100 Research Drive
Worcester, MA 01605 USA