[ccp4bb]: Biochemistry Research Associate at Abbott Bioresearch Center, Inc.

[David W Borhani <borhand@basf-corp.com>]

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Research Associate - Biochemistry (Position Code: Biochem 03)

A new research associate position is available in the structural biology group
at Abbott Bioresearch Center in Worcester, MA, located 45 minutes west of
Boston. Abbott Bioresearch Center, a division of Abbott Laboratories, has
vibrant research programs on traditional, low molecular weight pharmaceuticals
and fully-human, monoclonal antibody pharma-ceuticals in the immunology and
oncology therapeutic areas. The structural biology group is fully-integrated
into the drug design process at ABC, and exciting opportunities for both
scientific and career development exist.

The  successful candidate will conduct protein purification and characterization
in  support  of  structural  biology  efforts.  Assistance in the development or
execution  of  enzyme  assays will likely be required. The opportunity exists to
become  involved  in  protein  crystal growth experiments. Requirements: B.S. or
M.S.  in Biochemistry, Chemistry, Molecular Biology, or equivalent. At least one
year   of   hands-on   laboratory   experience   in   protein  purification  and
characterization,  including  affinity chromatography, and basic enzyme kinetics
is  required. Experience in simple molecular biology techniques and fermentation
(E.   coli,  yeast,  baculovirus)  is  a  plus,  as  is  experience  in  protein
crystallization.  Experience in a pharmaceutical or biotechnology environment is
especially helpful.

The  protein crystallography laboratory at Abbott Bioresearch Center is equipped
with  a  Nonius  FR571  x-ray  generator, MarResearch CCD and MAR345 image plate
detectors,  Osmic optics, and Oxford Cryostream cryogenics. We also have routine
access to the IMCA-CAT beamlines at the Advanced Photon Source, Argonne National
Laboratory.  Ample  computational  resources  are  available, and the structural
biology  group  at ABC is committed, along with our sister group at Abbott Park,
IL,   to   the   automation   of   the   routine  crystallographic  tasks  using
state-of-the-art robotic systems.

Applicants  should  submit  their  curriculum  vitae,  listing names and contact
information  for  three  references,  by  e-mail to worcesterjobs@abbott.com (MS
Word,  PDF, or plain text, please), ensuring that the Position Code "Biochem 03"
and "David Borhani" are prominent in the Subject line.

David Borhani
Group Leader, Biochemistry
Abbott Bioresearch Center, Inc.
100 Research Drive
Worcester, MA 01605 USA
508-849-2944