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[ccp4bb]: ++
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Could someone please explain how dmmulti works. I have 4 weak
(different) Hg derivatives that are matched against 1 of 3
natives (on the basis of agreement of length of C axis). All
4 have one site in common and 3 have a 2nd site in common.
I have applied (individually) solve and resolve and then
put the whole bunch through dmmulti to supposedly get a better
map than any of the individual maps.
My thinking was that dmmulti would conceptually build and
refine a concensus electron density map and then x-form
this map back to each of the individual cells (in this
case trivially since the operator would essentially be the
identity) then back transform each of these to get phase & fom
for each data set.
However, when I calculate the correlation between pairs I get
a highest value of .75 with the rest .62-.68. I did have to
fudge the cell constants because mapman requires identical
cell params. Are the CC a bit low because of the fudging
of the cell params or am I wrong to think that all of the
dmmulti maps should be nearly identical? If I am wrong
do I STILL need to combine the maps (or phases) somehow
in order to get as much information into a single map as is
possible?
TIA
Steve Ernst