[ccp4bb]: CCP4 2002 Study Weekend

[Alun Ashton <A.W.Ashton@dl.ac.uk>]

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           High-throughput Structure Determination
  A meeting organised by CCP4 and Daresbury Laboratory
                  4-5th January 2002
                The University of York


The high-throughput revolution that swept through DNA sequencing and
genetics is set to change the face of structural biology. This study
weekend will address all aspects of this revolution from target selection
and protein production through data collection and processing to model
building and validation.

With automation comes miniaturisation, posing further challenges. Setting
up small-volume crystallisation plates, warehousing the trials and
inspecting the millions of drops for crystal growth all pose their own
problems. In particular, the methods for determining if a drop contains a
crystal are still in their infancy.

Once diffraction quality crystals are produced the focus shifts to the
synchrotrons where MAD/SAD strategies, efforts to automate sample
changing, data collection, processing and phasing are already starting to
deliver structure determination in hours. Computation underpins all
aspects of structural genomics from target selection, laboratory
automation and information management, crystal detection, data collection
and phasing to model building, validation and analysis.

The annotation of genomic data with structural (and functional)
information is a major challenge for structural biologists and this study
weekend will provide a timely update for this rapidly emerging field.



Invited speakers include:
     Jan-Pieter Abrahams (Leiden, NL) 
     Paul Adams (Berkeley, USA)
     Allan Bradley,(Sanger Centre, UK)
     Carl Branden,(Stockholm, Sweden)
     Iain Campbel,(Oxford, UK)
     Chris Dobson,(Cambridge, UK)
     Tim Harris,(Structural GenomiX, USA)
     Fergal Hill,(Avidis, France)
     Alwyn Jones,(Uppsala, Sweden)
     Ian Jones,(Reading, UK)
     Andrew Leslie,(Cambridge, UK)
     Tom Terwilliger,(Los Alamos, USA)
     Andy Thompson,(Grenoble, France)
     Martyn Winn,(CCP4, UK)

How to apply:
For a web registration form and more details, visit the CCP4 WWW homepage
at http://www.ccp4.ac.uk/ and follow the courses link. 

Further enquiries can be made to ccp4conf@dl.ac.uk, Tel: +44 (0)1925
603929, Fax: +44 (0(1925 603825;  or to Maeri Howard Eales, Daresbury
Laboratory, Daresbury, Warrington WA4 4AD, UK


Scientific Organisers:Robert Esnouf and Dave Stuart (Oxford), Keith Wilson (York) 
Organisers: Alun Ashton, Maeri Howard Eales and Pat Broadhurst (Daresbury) 

Closing date for applications is 16 November 2001. Applications must be
received by this date. Early registration is recomended as numbers may
need to be limited.