[ccp4bb]: Hole in a needle-like crystal

[Kaoru Mitsuoka <kaorum@em.biophys.kyoto-u.ac.jp>]

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Dear All,

This is not exactly a CCP4-related topic but I think that someone can
answer my question.

One of my colleagues is working on three-dimnesional crystals of GFP.
(He is not a crystallographer.)  In the polarized microscope, the
needle-like crystals show clear hole-like structure (dark core) in
the parallel direction to the longer axis.  Have someone experienced
a similar crystal?  If so, what is the explanation of the hole?
(Actual hole or nucleation part or others?)  Any suggestions are
welcome.

Thanking you in advance,
Kaoru Mitsuoka

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Dr Kaoru Mitsuoka (kaorum@em.biophys.kyoto-u.ac.jp)
Deparment of Biophysics, Faculty of Science, Kyoto University
Oiwake-cho, Kitashirakawa, Sakyo-ku, Kyoto, 606-8502 Japan
TEL +81-75-753-4216  FAX +81-75-753-4218
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