[ccp4bb]: REfmac message!

[<rams@poori.biochem.uiowa.edu>]

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Hello All,

I am at the end of refinement of my structure.  Things went great.
then now that my R-factors are 15.5 and Rfree is 17.0 (data to 1.1A
resolution) refined with anisotropic b factors, I am suddenly getting

 Problem in MAKE_U_POSITIVE -0.1387620

How do I find out the offending atom(s) - or did something else go crazy.
The geometry are all well behaved.  I have 8 Zn+2 in my structure and
their equivalent isotropic B's are positive.....

Thanks.

Rams.


-- 
S. Ramaswamy
Department of Biochemistry.
University of Iowa.