Re: [ccp4bb]: Residue movements at 100K?

[Bart Hazes <bhazes@ualberta.ca>]

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In cases of radiation damage to frozen crystals you sometimes see a
single-conformation cystine adopt a dual conformation. So there is sidechain
motion there. I can also imagine that sidechains pointing into a cavity, or
even elsewhere, would still be able to move. It depends on the activation
energy barrier. The real problem is how do you know it is moving at 100K
rather than having "frozen in" a bunch of conformations that were in existence
at room temperature prior to freezing.

On Tue, 7 May 2002, Paula Lario wrote:

>
> Hello All,
>
> I was wondering if anyone has evidence for side chain movements
> occurring
> in a frozen crystal (@ 100K) or if anyone believes that it is possible.
>
>
> --
> ~~~~~~~~~~~~~~~~~~~~~~~~~~
> Paula Lario
> McGill University / UCSC
> Nothing is ours, but time.
>
>
>

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