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[ccp4bb]: Hydrophobic protein



Sorry this is not directly CCP4 related!
I am handling some tricky protein which have lots of hydrophobic residues. I am expecting that many of them are located on the surface. Therefore, proteins are precipicated one or two days after purification.  Could you please send me some advices to stabilize the hydrophobic surface of the protein?
 
 
Sincerely yours,
 
Kyeong Kyu Kim
Sungkyunkwan University School of Medicine
Suwon, Korea