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Re: [ccp4bb]: How to deal with sidechainatoms with low electrondensity ... offon a tangent ...
Probably best not to start a flaming war...but maybe no NMR people subscribe to this bulletin board?
I think it boils down to whether enough NOE's are observed (or not) to tie down the conformation/position (or not) of atom(s), vs. measurements of T1 or T2 (I forget which), which speak directly to the mobility of an atom(s).
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David Borhani
Group Leader, Biochemistry
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