[ccp4bb]: Useful CA-models

[Patrick Cramer <cramer@lmb.uni-muenchen.de>]

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Dear all

There is a long list of correct and useful backbone models.

Technical difficulties with multi-macromolecular complexes
often allow only for modeling of the backbones. It is these
large complexes that are of great interest for understanding
cellular function. Any detailed structural information helps.
Backbone models can be checked in various ways and in
favorable cases reveal the location of individual residues,
giving them great explainatory and predictive power.

I wish to add to the list of examples the backbone model of
RNA polymerase II (Science 288, 640-649, 2000) that was
confimed later with a refined 2.8 A model. In this case,
one purpose of the backbone model was to make the
information available to the large transcription community
immediately, as structural information was long awaited
and it was unclear how long it would take to arrive at an
atomic model.

Patrick Cramer