[ccp4bb]: ccp4-4.2.2 - linux and refmac

[<rams@poori.biochem.uiowa.edu>]

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Garib and all!

I have always kept the hydrogens on in all my refinements using refmac.  
Starting with refmac 5.1.24 however, refmac behaves very badly if do 
generate all hydrogens.  My R-factors go up like crazy and lots of 
complaints on uncorrect -H distances.... I initially panicked, but later 
switched off the H generation with "ignore even if present in file" and 
everything works fine.  IS this a Linux specific bug or am I doing 
something wrong. I have tried with all kinds of resolution structures 
starting from 2.1 - 1.4...

Thanks.

Rams.


-- 
S. Ramaswamy
Department of Biochemistry.
University of Iowa.