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[ccp4bb]: detwinning anomalous data



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I have been having lots of trouble with 50% twinning for a Se-met
derivative that I am working on.  Recently I have collected a data set
which appears to be less twinned (33%).  I would like to attempt to detwin
this data set but keep the anomalous signal.  Is it a good idea to
seperate the F+ and F-, detwin and then join them back together if so how
do I join them back together to create a normal mtz file with FP, DANO
etc.

any help would be greatly appreciated
        thanks
                Ambrose