The Karle-Hauptman matrix of a set of unitary structure factors
can be defined as follows,

or,

where
, and conventionally
.
Consider the product of two Karle-Hauptman matrices of
and
, where
.

If enough reflections are included in the Karle-Hauptman determinant, the
summation over
becomes the Fourier inversion formula
for
, thus:

If
, then:

i.e.
is the inverse of
. Thus, if enough terms
are included, the Karle-Hauptman matrix associated with the inverse of
an electron density function is the inverse of the Karle-Hauptman
matrix associated with the electron density function itself.