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[ccp4bb]: Re: (fwd)



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> Any ideas out there how fast the conformations of side chain
> double conformations might interchange ? More specifically:
> How often (per second) hops the side chain
> from conformation one into the other or back.
> Please, refer to  literature.

You start by making the assumption that the disorder is dynamic, ie they do hop a
few times per second, while the disorder might well be (and is in many cases)
static.

Tried a PUBMED search first ?

    A.

In a data set of bragg intensities collected at room temperature
there is nothing that justifies an assumption that the disorder is static, as
well as there is nothing that justifies an assumption that the disorder is
dynamic. However, at very low temperature it is clear that a double conformation
is static. So, again, the question to all structural MD gurus. What is the typical 
frequency of a transition between double conformations at room temp ? 


Marius