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[ccp4bb]: Examples of pH affecting ligand conformation wanted



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Does anybody know of any published example of a case where
pH affects the observed conformation of a cocrystallised
ligand ? I.e., the same ligand in complex with the same
protein assumes different conformations at different pH
levels.

Replies directly to me please, not to the mailing list(s).

Thanks !!

--Gerard

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                        Gerard J.  Kleywegt
    [Research Fellow of the Royal  Swedish Academy of Sciences]
Dept. of Cell & Molecular Biology  University of Uppsala
                Biomedical Centre  Box 596
                SE-751 24 Uppsala  SWEDEN

    http://xray.bmc.uu.se/gerard/  mailto:gerard@xray.bmc.uu.se
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