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N. Gautham wrote:
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> Hello all,
> This is a general MR question. Can some one enlighten me on the
> relationship, if any, between the resolution of the data and the
> accuracy of the model used in MR. For example, if I use only low
> resolution data say 6.0 A to calculate the rotn. fn., etc, can I get
> results by using a model that has rmsd of say 6.0 A from the 'true'
> structure? Any references, comments would be welcome. Thanks.
As far as I know there is no known case of MR solution at any resolution
from a coordinate model with rmsd of 6A.
But there are cases where EM maps have been fitted successfully against
However low homology models work better with lower resolution data, but
I tend to use cut offs of 2.5A for a near perfect model, and 4A for a
low homology one..
At 6A there may well be other problems - results can be influenced by %
of solvent, crystal symmetry, etc etc etc..
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